MyoBlox Contra (Lean Muscle / Anti Estrogen) Myo-blox

N-COURMAROYLDOPAMINE:
N-coumaroyldopamine is a naturally occurring beta-2 adrenergic receptor agonist that is extracted from Theobroma cacao seems to have an effect in the 20-40mg/d range.

PIPERINE (BLACK PEPPER EXTRACT):
Derived from peppercorns from Piper Nigrum Plants, Bioperine® is a patented extract that is used as a bioavailability enhancer of numerous nutrients via stimulation of the digestive tract. On top of its noted benefits Piperine may also have an indirect function to support  thermogenesis.†

NOTE: Contra is meant to be taken for up to 8-12 weeks before cycling off. For maximal benefits, Contra may be stacked with Mania.

SCIENTIFIC REFERENCES:

1. Chatterjee, Sandipan, et al. “Comprehensive metabolic fingerprinting of Withania somnifera leaf and root extracts.” Phytochemistry10 (2010): 1085-1094.
2. Choudhary, Dnyanraj, Sauvik Bhattacharyya, and Kedar Joshi. “Body weight management in adults under chronic stress through treatment with Ashwagandha root extract: a double-blind, randomized, placebo-controlled trial.” Journal of evidence-based complementary & alternative medicine1 (2017): 96-106.
3. Mahdi, AA et al. Withania somnifera Improves Semen Quality in Stress-Related Male Fertility. Evidence-based Comp Alt Med. 2011
4. Wankhede, Sachin, et al. “Examining the effect of Withania somnifera supplementation on muscle strength and recovery: a randomized controlled trial.” Journal of the International Society of Sports Nutrition1 (2015): 43.
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7. Avvakumov GV, Grishkovskaya I, Muller YA, Hammond GL. Crystal structure of human sex hormone-binding globulin in complex with 2-methoxyestradiol reveals the molecular basis for high affinity interactions with C-2 derivatives of estradiol. J Biol Chem. 2002 Nov 22;277(47):45219-25
8. Franks S, MacLusky NJ, Naish SJ, Naftolin F. Actions of catechol oestrogens on concentrations of serum luteinizing hormone in the adult castrated rat: various effects of 4-hydroxyoestradiol and 2-hydroxyoestradiol. J Endocrinol. 1981 May;89(2):289-95.
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